Cellular Research · Popular
NAD+ — Research Compound
Nicotinamide adenine dinucleotide, a redox coenzyme studied as a cofactor in several hundred enzymatic reactions and as the substrate of sirtuin enzymes.
$59.99 · 500mg
Third-party tested · Freedom Diagnostics
View COA · Third-party COA · Lot EP-3359K
- Ships from within the U.S.
- Pay by card, Apple Pay, Venmo, Cash App or crypto
- Stored frozen at −10 °F until ship day
- Batch ID and QR code on the label
For in-vitro laboratory research use only. Not for human consumption.
Specifications
NAD+ at a glance.
- Size
- 500mg
- Form
- Lyophilized powder
- Storage
- −20°C (Protected from light and moisture)
- Purity
- 99.87% (HPLC-UV · Freedom Diagnostics COA)
- Molecular weight
- 663.43 g/mol
- Molecular formula
- C₂₁H₂₇N₇O₁₄P₂
- Certificate of Analysis
- Third-party tested (Lot EP-3359K · Freedom Diagnostics)
- Category
- Cellular Research
Third-party COA · Lot EP-3359K
Documented by a third-party lab.
Issued by Freedom Diagnostics Testing, an independent lab, with Excalibur Peptides as the client. It covers lot EP-3359K. The PDF here is the same report the lab hosts.
Independent verification
Verify on Freedom Diagnostics.
This NAD+ Certificate of Analysis is hosted on Freedom Diagnostics Testing's own site. Search the code below on the lab's lookup page, or open the lab-hosted PDF. Values are shown as printed on the certificate.
Search code: Exca2610050651
- Lab
- Freedom Diagnostics Testing
- Lot
- EP-3359K
- Sample
- NAD+ 500mg
- Received
- 10/5/2026
- Reported
- 10/6/2026
- Purity (HPLC-UV)
- 99.87%
- Identity (LC-MS)
- Confirmed
- Net content
- 538.42 mg
View lab-hosted COA (PDF on coas.freedomdiagnosticstesting.com)
Previous reports
Previous batch — not the batch currently shipping
Third-party reports for earlier batches of NAD+, kept for transparency. Values as printed on each report.
- Received
- 06/09/2026
- Lab
- Freedom Diagnostics Testing
- Lot (cap colour)
- Green Cap
- HPLC purity
- 99.79%
What's in the box
One vial, part by part.
500mg of NAD+, supplied as a lyophilized powder in a sealed glass vial.
On the label
Clearly labeled.
Printed label
Product name, size and a research-use-only statement.
Batch ID
A batch number is printed on every label.
QR code
Printed on the label, next to the batch ID.
Research-use line
“For research and laboratory use only — not for human consumption” runs along the bottom of the label.
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Research
Research background.
Chemical identity, proposed mechanism and published preclinical literature, for laboratory reference.
Mechanism of action
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell. It acts as an electron carrier in redox reactions, including those of the mitochondrial electron transport chain, and is the substrate consumed by sirtuins (SIRT1-7), PARP enzymes of the DNA damage response and CD38. Its interactions with the CLOCK/BMAL1 circadian machinery have also been described in published research.
Research observations
- Cofactor for several hundred enzymatic redox reactions
- Substrate for sirtuin and PARP enzymes examined in in-vitro enzyme assays
- NAD+/NADH ratio measured as a readout in published cell-culture research
- Distinguishable from the reduced form (NADH) by UV absorbance at 340 nm
- Salvage and de novo biosynthesis pathways described in published biochemical research
Key research & publications
- Yoshino et al. (2018) — Review of NAD+ biosynthetic intermediates and their biochemistry.
- Rajman et al. (2018) — Review of published in vivo research on NAD+ precursor molecules.
- Imai & Guarente (2014) — Review of NAD+ and sirtuin biology.
Further reading
A longer overview of published NAD+ coenzyme literature, in our 2026 guide.
Frequently asked questions.
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide, C₂₁H₂₇N₇O₁₄P₂) is a redox coenzyme, not a peptide. It carries electrons in redox reactions and is the substrate consumed by sirtuin and PARP enzymes, which makes it a standard reagent in in-vitro enzyme assays.
Where can I buy NAD+ for research?
Excalibur Peptides sells NAD+ on this page as a 500mg vial of lyophilized powder, for in-vitro laboratory research only. Orders ship from Austin, Texas, to addresses within the United States, and the product's third-party Certificate of Analysis is published in our COA database. Buyers must be 21 or older and confirm research-use-only status at checkout.
How is NAD+ tested, and where is its COA?
NAD+ is third-party tested by Freedom Diagnostics Testing: purity by HPLC and identity by LC-MS. The Certificate of Analysis is published in our COA database, and the report can be looked up on the lab's own site with search code Exca2610050651.
How should NAD+ be stored in the lab?
Keep lyophilized NAD+ sealed at −20 °C, protected from light and moisture, as listed on this page. Let the vial reach room temperature before opening so moisture does not condense on the powder, and avoid repeated freeze–thaw cycles.
How fast does NAD+ ship?
NAD+ ships from Austin, Texas. Orders placed before 2 PM EST on a business day ship the same day, and delivery within the United States typically takes 2–4 business days. A tracking number is emailed when the order ships.
What payment methods can I use to buy NAD+?
We accept credit and debit cards, Apple Pay, Venmo, Cash App and cryptocurrency. Prices are in U.S. dollars.
Is NAD+ approved by the FDA?
No. The NAD+ supplied by Excalibur Peptides is not approved by the FDA for human or veterinary use. It is sold only for in-vitro laboratory research and identification purposes and is not for human consumption.
For research and laboratory use only. Not for human consumption.
All products sold on this website are intended for in-vitro laboratory research and identification purposes only. They are not for human or veterinary use and are not for human consumption.
All information is provided for educational and research purposes. Excalibur Peptides does not condone or promote the use of any product for any purpose other than legitimate scientific research and compound identification.