BPC-157 — Research Peptide

BPC-157: Research Overview

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide whose sequence corresponds to a fragment of a protein first described in gastric juice. Composed of 15 amino acids (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val), BPC-157 has been the subject of published preclinical research since the early 1990s, with in-vitro and animal studies examining its interactions with cell signaling pathways.

Research has focused primarily on BPC-157's interaction with the nitric oxide system and on signaling pathways such as FAK–paxillin and VEGFR2–Akt–eNOS. Studies in cultured cells have examined cell migration, receptor expression and growth-factor signaling, while animal studies have examined the peptide in gastrointestinal and connective-tissue models.

A further area of BPC-157 research involves the gut-brain axis, where rodent studies have examined its influence on serotonin and dopamine neurotransmission. All findings to date originate from in vitro and animal models. BPC-157 is not approved for human use and is supplied for in-vitro laboratory research only.

Research Applications

• FAK–paxillin signaling — examined in published cultured-fibroblast studies
• Nitric oxide system — interactions with NO synthesis examined in published cell and animal research
• VEGFR2–Akt–eNOS signaling — examined in published endothelial cell models
• Growth hormone receptor expression — examined in cultured fibroblasts exposed to BPC-157
• Gastrointestinal models — BPC-157 has been examined in published rodent gastrointestinal research
• Dopaminergic and serotonergic signaling — examined in published rodent studies
• Peptide stability — behavior in acidic, gastric-juice-like media characterized in published stability work

Laboratory Handling and Regulatory Status

BPC-157 is supplied as a lyophilized powder. Store it sealed at −20°C, protected from light and moisture, and allow the vial to reach room temperature before opening to limit condensation. Its calculated molecular mass is about 1,419.5 Da. Purity is assessed by HPLC and identity by LC-MS (Freedom Diagnostics Testing); a Certificate of Analysis is published for this product on our COA page.

No regulatory authority has approved BPC-157 for human or veterinary use. It is sold as a research chemical for in-vitro laboratory research and identification purposes only. Researchers should follow all applicable institutional guidelines when working with this compound.

Frequently Asked Questions

Where does the BPC-157 sequence come from?

BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide whose sequence corresponds to a fragment of a protein first described in gastric juice. It is used exclusively as a research chemical in preclinical studies and is not approved for human use.

Which signaling pathways has BPC-157 been examined in?

Published in-vitro and animal research has examined BPC-157 in relation to the nitric oxide (NO) system, the FAK–paxillin pathway, VEGFR2–Akt–eNOS signaling, and dopaminergic and serotonergic neurotransmission.

What kind of research has BPC-157 been examined in?

BPC-157 has been examined in published cell-culture studies and rodent models, including gastrointestinal and connective-tissue models. Published work is preclinical; the compound is supplied for in-vitro laboratory research only.

Is BPC-157 the same as Body Protection Compound?

Yes. BPC-157 is the abbreviation for Body Protection Compound-157, referring specifically to the 15-amino-acid synthetic sequence used in research.

For research purposes only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.